Protocol: Microneediling, in Treatment Room

[Before Treatment Consultation & Assessment ]

• History of oral herpes labialis: In these patients, a 1-week course of oral antiviral

therapy is recommended as a prophylactic measure (starting on the day of treatment)

to minimize this complication.

• It is recommended to avoid treatment in patients with active acne or other

inflammatory lesions.

• Microneedling on any inflammatory acneiform lesion may predispose the patient to

the development of microabscesses or bacterial granulomas

1. Cleanse the skin thoroughly.

2. Apply topical anesthetic (usually lidocaine-based) for 20-30 minutes. Remove with

gauze soaked in water and an alcohol preparation.

3. Retrieve product from the refrigerator.

4. Pour the liquid diluent into the lyophilized (freeze-dried) exosomes. Close and shake

the bottle five or six times until perfectly combined. This product is not toxic but is

wasted if applied directly onto an ungloved hand. Gently pull the skin with one hand

and simultaneously lower the microneedling device perpendicular to the skin with the

other hand.

5. Apply sufficient Exotop solution to the surface of the treatment area to facilitate the

gliding action of the device (pea size amount per zone to treat recommended)

6. Combine horizontal, vertical and oblique passes of the device over the treatment

areas, repeating approximately 3 to 6 times, or until a fine pinpoint bleed is observed

Initial Protocol: 3–6 sessions, spaced 2–4 weeks apart.

Maintenance: Every 3–6 months, depending on skin/hair response